Activity | |||
---|---|---|---|
5 μM | 100 μM | ||
pmol/min/mg microsomal protein | |||
Wild type | 2.575 ± 0.205 | 11.78 ± 1.289 | |
Pro42Arg | N.D.*** | 0.466 ± 0.057*** | |
Arg377Gln | N.D.*** | N.D.*** | |
Arg456His | N.D.*** | 0.377 ± 0.083*** |
N.D., not detectable. Detection limit, 0.16 pmol/min/mg microsomal protein.
↵*** P < 0.001 compared with the wild type.