TABLE 3

Thermodynamic parameters for the hydrolysis of CS-866 and PNPA by HSA


Substrate

ΔGT

ΔGS

ΔG

ΔH

ΔS
kJ · mol-1 kJ · mol-1 kJ · mol-1 kJ · mol-1 kJ · mol-1 · K-1
CS-866 71.3 -25.0 96.3 34.7 -0.207
PNPAa
58.1
-20.9
79.0
66.1
-0.0435
  • a PNPA data from Sakurai et al. (2004). Reaction conditions: 1/15 M phosphate buffer (pH 7.4), 25°C.