TABLE 1

Time course of radioactivity in the liver of rats following an intravenous dose of 2 mg/kg [3H]caspofungin

The values are presented as mean percentage (n = 2–4) of dose in the liver.


Time (h)

Radioactivity in the Liver (% of Dose)
0.5 8.4
1 12.0
2 14.4
6 26.8
12 32.5
24 39.2
48 35.4
120 14.2
288
2.8