Comparison of CYP3A inactivation between HLM-predicted potency and the potency observed in cryopreserved human hepatocytes
N.C., not calculated.
↵ a Obtained from eqs. 2 and 3 using HLM parameters
↵ b Iu that is required to produce 50% inactivation observed in hepatocytes
↵ c [Ī] used for the determination of IC50, Corrected