TABLE 1

LC-MS/MS parameters for analysis of NSAID glucuronides


Glucuronide

Elution Time

Parent Ion

Daughter Ion

Detection Limit
min m/z ng
Sulindac 2.4 531 193 0.2
Sulindac sulfone 2.9 547 193 0.2
Indomethacin 4.1 532 193 0.5
Ibuprofen 3.4 381 193 0.5
Flurbiprofen 2.3 419 193 2
Ketoprofen 2.2 429 193 1
Diclofenac 2.1 405 193 0.5
Naproxen
2.4
470
193
0.5