The number of receptor-activating chemicals in a class that alter mRNA expression of Mrps after treatment
AhR | PXR | CAR | PPARα | NRF2 | |
|---|---|---|---|---|---|
| Mrp1 | ↓ (2/3) | ↓ (1/3) | |||
| Mrp2 | ↑ (3/3) | ↓ (2/3) | ↑ (1/3) | ↑ (2/3) | |
| Mrp3 | ↑ (3/3) | ↑ (2/3) | ↑ (3/3) | ↑ (3/3) | ↑ (3/3) |
| Mrp4 | ↑ (1/3) | ↑ (3/3) | |||
| Mrp5 | ↑ (3/3) | ↑ (2/3) | ↑ (3/3) | ||
| Mrp6 | ↑ (3/3) | ↑ (2/3) | ↑ (3/3) | ||
| Mrp7 | ↑ (3/3) | ↑ (3/3) | ↑ (1/3) | ||
| Mrp9 | ↓ (1/3) |
|
| ↓ (2/3) | ↓ (1/3) |