Sum of CYP2B6 and 3A4 % TNRs vs. % I with ketoconazole and ticlopidine
Comparison between the sum of % TNRs of CYP2B6 and CYP3A4 in the metabolism of endosulfan-α and % I with ketoconazole and ticlopidine in the same incubation. With the exception of HK23, the other five HLMs had matching % TNR and % I.
HLM | % TNR | % I |
|---|---|---|
| HG3 | 94 | 92 |
| HG112 | 93 | 88 |
| HG42 | 96 | 92 |
| HK23 | 84 | 57 |
| HG43 | 78 | 85 |
| HG93 | 86 | 76 |