Sequence comparisons between CYP3A64 and other cytochromes P450 from the CYP3A subfamily
The amino acid sequence of CYP3A64 was aligned with other members of the CYP3A subfamily and the percentage identity was calculated using CLUSTALW (http://www.ebi.ac.uk/clustalw/).
Cytochrome P450a | Species | Protein | Nucleotide | |
|---|---|---|---|---|
| % identity | ||||
| CYP3A8 | Cynomolgus monkey | 100 | 99 | |
| CYP3A4 | Human | 93 | 95 | |
| CYP3A5 | Human | 83 | 88 | |
| CYP3A12 | Beagle dog | 77 | 82 | |
| CYP3A26 | Beagle dog | 75 | 82 | |
| CYP3A2 | Sprague-Dawley rat | 70 | 76 | |
| CYP3A1 | Sprague-Dawley rat | 71 | 76 | |
| CYP3A6 | New Zealand White rabbit | 74 | 80 | |
↵ a Amino acid sequences for the various CYP3A enzymes were obtained from Entrez, the database search and retrieval system at the National Center for Biotechnology Information (http://www.ncbi.nlm.nih.gov).