Parameters | Dose | ||||
---|---|---|---|---|---|
10 mg/kg | 3 mg/kg | 0.1 mg/kg | |||
AUC (μg · min/ml) | 2497 ± 544 | 664 ± 123 | 21.1 ± 7.2 | ||
t1/2 (min) | 242 ± 42 | 213 ± 34 | 143 ± 97 | ||
CL (ml/min/kg) | 4.2 ± 0.9 | 4.6 ± 0.9 | 5.2 ± 1.9 | ||
Vss (l/kg)
| 1.4 ± 0.3 | 1.4 ± 0.3 | 1.3 ± 0.5 |