Body and liver weights, microsomal protein in the liver, and plasma thyroid hormone concentrations in pigs fed a control diet or a diet supplemented with 5 g of clofibrate/kg for 28 days
Data are reported as mean ± S.D. with nine animals per group.
Control | Clofibrate | |
|---|---|---|
| Initial body weight (kg) | 12.0 ± 1.1 | 11.9 ± 0.6 |
| Final body weight (kg) | 26.0 ± 1.5 | 25.2 ± 1.2 |
| Liver weight (g) | 673 ± 63 | 779 ± 63a |
| Hepatic microsomal proteins (mg/g liver) | 12.4 ± 1.8 | 15.4 ± 2.4a |
| Plasma thyroid hormones | ||
| Total thyroxine (T4, nM) | 45.2 ± 13.1 | 29.6 ± 7.1a |
| Free thyroxine (pM) | 12.6 ± 3.7 | 8.6 ± 2.2a |
| Total triiodothyronine (T3, nM) | 1.20 ± 0.52 | 0.64 ± 0.11a |
| T4/T3 ratio | 41.1 ± 13.2 | 40.3 ± 10.7 |
↵ a P < 0.05 compared with control group.