TABLE 4

Relative hepatic mRNA concentrations of transthyretin, thyroxine-binding globulin, albumin, thyroid hormone receptor α1, and type I iodothyronine deiodinase in pigs fed a control diet or a diet supplemented with 5 g of clofibrate/kg for 28 days

Data are reported as mean ± S.D. with nine animals per group. All the mRNA concentrations were determined by semiquantitative RT-PCR and normalized by GAPDH. Data are expressed relative to mRNA concentrations of control pigs (control = 1).




Control

Clofibrate
Transthyretin 1.00 ± 0.14 0.87 ± 0.12a
Thyroxine-binding globulin 1.00 ± 0.14 0.89 ± 0.18b
Albumin 1.00 ± 0.11 0.87 ± 0.11a
Thyroid hormone receptor α1 1.00 ± 0.14 0.84 ± 0.10a
Type I iodothyronine deiodinase
1.00 ± 0.07
0.98 ± 0.07
  • a P < 0.05 compared with control group.

  • b P < 0.10 compared with control group.