TABLE 3

r2 values obtained from the linear regression of the Ki values for two probes using CYP2C9.1




Diclofenac

Flurbiprofen

Warfarin

Phenytoin

Tolbutamide
Substrate
Diclofenac 1
Flurbiprofen 0.66 1
Warfarin 0.76 0.69 1
Phenytoin 0.92 0.62 0.73 1
Tolbutamide
0.95
0.61
0.68
0.92
1