TABLE 4

r2 values obtained from the linear regression of the Ki values for two probes using CYP2C9.3




Diclofenac

Flurbiprofen

Warfarin

Phenytoin

Tolbutamide
Substrate
Diclofenac 1
Flurbiprofen 0.74 1
Warfarin 0.84 0.69 1
Phenytoin 0.88 0.80 0.78 1
Tolbutamide
0.92
0.77
0.83
0.88
1