Pharmacokinetic parameters of Ber and its metabolites (total contents) in conventional (CON) and pseudo germ-free (GF) rats after administration of 40 mg/kg p.o. Ber
Pharmacokinetic Parameters | |||
|---|---|---|---|
| AUC0-limt | MTT | ||
| ng · h · ml-1 | h | ||
| Ber (CON) | 37.42 | 10.53 | |
| Ber (GF) | 40.89 | 10.25 | |
| M1 (CON) | 1879.64 | 18.32 | |
| M1 (GF) | 437.29 | 7.45 | |
| M2 (CON) | 811.05 | 7.62 | |
| M2 (GF) | 287.85 | 4.84 | |
| M3 (CON) | 1763.62 | 24.68 | |
| M3 (GF) | 735.22 | 15.08 | |
| M4 (CON) | 356.05 | 10.32 | |
| M4 (GF) | 101.98 | 4.05 | |