TABLE 1

Effect of SNP and IL-6 on CYP1A2 and CYP3A6 activities, assessed after 4 and 24 h of incubation with H_CONT and H_TIIR

	CYP1A2			CYP3A6
	4 h	24 h	4 h	24 h
H_CONT	9363 ± 578^a	8617 ± 511	11,989 ± 1001	7013 ± 703
H_CONT + SNP	4793 ± 942^b	3142 ± 1280^b	2085 ± 1243^b	444 ± 50^b
H_CONT + IL-6	7971 ± 674^b	6232 ± 1112^b	10,947 ± 869	6268 ± 760
H_TIIR	1905 ± 253	1680 ± 147	1478 ± 147	972 ± 137
H_TIIR + SNP	1672 ± 434^c	1157 ± 72^c	694 ± 71^c	311 ± 33^c
H_TIIR + IL-6	1845 ± 238	1524 ± 117^c	1227 ± 176^c	851 ± 125^c

↵ a Fluorescence arbitrary units.
↵ b,c p < 0.05 compared with H_CONT or H_TIIR, respectively.