TABLE 5
Percentage of calculable f values in the different cell lines
Cell System
Percentage of P-gp-Inhibiting Compounds Not Reaching
f
2
f
3
f
4
P388/dx
7.5
22.5
50.0
L-MDR1
20.8
52.1
56.3
pBCECs
13.5
43.2
59.5