TABLE 1

Percentage of dose distributed into different tissues 2 h after intravenous administration of [1,2-3H]MF in male Sprague-Dawley rats


Tissue

% of Dose (n = 3)
Brain 0.05 ± 0.01
Thymus 0.09 ± 0.03
Heart 0.07 ± 0.02
Spleen 0.27 ± 0.11
Lung 0.35 ± 0.03
Kidney 0.28 ± 0.04
Stomach 1.22 ± 0.32
Liver 1.99 ± 1.18
Large intestine 2.45 ± 1.77
Small intestine 4.51 ± 0.10
Intestinal contents 81.47 ± 5.69
Muscle 0.21 ± 0.06a
Fat 0.41 ± 0.18a
Skin 0.05 ± 0.02b
Plasma 0.25 ± 0.07c
Urine
0.08 ± 0.02c
  • a Percentage of dose per gram of tissue.

  • b Percentage of dose per square centimeter.

  • c Percentage of dose per milliliter.