Comparison of the fragments in the daughter mass spectrum between the subject metabolite and TAS-108 and its known metabolites
The daughter mass spectra of TAS-108 and its known metabolites were obtained with a Finnigan TSQ 7000 detector (Thermo Electron Corporation) according to the description under Materials and Methods.
The Subjective Metabolite | The Subjective Metabolite [M + 4] | TAS-108 | deEt-TAS-108 | TAS-108-N-Oxide | |
|---|---|---|---|---|---|
| Q1 | 491 (477 + 14) | 495 (491 + 4) | 509 | 477 | 528 |
| F1 | 137 | 137 | 137 | 137 | 137 |
| F2 | 161 (147 + 14) | 161 | 147 | 147 | 147 |
| F3 | 187 (173 + 14) | 187 | 173 | 173 | 173 |
| F4 | 311 (277 + 14) | 315 (311 + 4) | 277 | 277 | 277 |
| F5 | 447 (433 + 14) | 451 (447 + 4) | 433 | 433 | 433 |