Metabolite | Percentage Excreted | ||||
---|---|---|---|---|---|
Urine | Feces | Total | |||
M2 | 0.1 ± 0.0 | 4.7 ± 1.0 | 4.9 ± 1.0 | ||
M3 | 0.5 ± 0.1 | 1.1 ± 0.6 | 1.5 ± 0.7 | ||
M6 | 0.4 ± 0.3 | 20.6 ± 4.4 | 21.0 ± 4.6 | ||
M7 | 0.3 ± 0.1 | 1.6 ± 0.4 | 1.9 ± 0.3 | ||
M8 | 0.2 ± 0.1 | N.D. | 0.2 ± 0.1 | ||
M9 | 0.6 ± 0.3 | N.D. | 0.6 ± 0.3 | ||
M10 | 0.1 ± 0.0 | N.D. | 0.1 ± 0.0 | ||
M11 | 2.2 ± 0.9 | 27.2 ± 6.0 | 29.4 ± 6.1 | ||
M12 | 0.1 ± 0.1 | 1.0 ± 0.3 | 1.1 ± 0.4 | ||
M13 | 0.0 ± 0.0 | 1.7 ± 0.8 | 1.7 ± 0.8 | ||
M14 | 0.2 ± 0.1 | 3.0 ± 1.1 | 3.2 ± 1.1 | ||
M16 | N.D. | 9.6 ± 3.7 | 9.6 ± 3.7 | ||
M17 | N.D. | 3.2 ± 0.8 | 3.2 ± 0.8 | ||
M18 | 0.3 ± 0.1 | N.D. | 0.3 ± 0.1 | ||
Erlotinib | 0.3 ± 0.2 | 1.0 ± 0.3 | 1.3 ± 0.5 | ||
Total Dose Identified | 5.3 ± 1.6 | 75 ± 7.9 | 80 ± 8.8 | ||
Total Dose Pooled | 5.9 | 79.5 | 85.4 |
a N.D., not detectable.