Group | Compound | Dose | Tmax | Cmax | F |
---|---|---|---|---|---|
μmol/kg | h | μM | % | ||
Active | MGS0039 | 26.4 | 1.3 ± 0.6 | 0.8 ± 0.5 | 12.6 |
B | MGS0111 | 23.3 | 3.3 ± 1.2 | 1.3 ± 0.6 | 16.9 |
MGS0096 | 22.6 | 2.0 ± 0.0 | 1.4 ± 0.2 | 10.3 | |
MGS0113 | 21.2 | 2.7 ± 1.2 | 4.0 ± 1.0 | 29.7 | |
MGS0155 | 22.3 | 3.3 ± 1.2 | 3.3 ± 0.7 | 32.9 | |
MGS0201 | 21.6 | 2.3 ± 1.5 | 3.3 ± 1.4 | 30.9 | |
MGS0210 | 21.0 | 3.7 ± 3.8 | 4.0 ± 1.6 | 38.6 | |
MGS0209 | 20.4 | 1.3 ± 0.6 | 2.3 ± 0.6 | 25.2 | |
C | MGS0116 | 21.2 | 4.7 ± 3.1 | 3.8 ± 1.0 | 50.7 |
MGS0200 | 22.3 | 2.0 ± 0.0 | 5.0 ± 1.8 | 44.5 | |
MGS0212 | 21.0 | 4.3 ± 3.5 | 2.7 ± 0.3 | 44.0 | |
| MGS0213 | 21.6 | 2.0 ± 0.0 | 2.8 ± 0.6 | 21.8 |