TABLE 6

Propofol (100 μM) inhibition of glucuronidation of JNJ-10198409 in HLM

Drug Concentration
Glu-A Formationa
Glu-B Formationa
%
0 μM 100 100
1 μM 11 13
5 μM 87 93
25 μM
104
107

  • ↵ a Glucuronide formation was expressed relative to the control group (no inhibitor).