TABLE 1

Biliary secretory function Results are expressed as mean ± S.D. (n = 3).

Control
EE
Bile flow (μl/min/g liver) 2.00 ± 0.17 0.98 ± 0.41*
Bile salt secretory rate (nmol/min/g liver) 58.2 ± 9.7 36.7 ± 15.1*
Biliary excretion of total glutathione (nmol/min/g liver) 2.53 ± 0.46 0.38 ± 0.26*
Hepatic content of total glutathione (nmol/g liver)
5984 ± 562
5391 ± 773

  • ↵* Significantly different from control group (P < 0.05)