TABLE 2

Effect of GAL on the alterations induced by EE on SRM of TUDC SRM of TUDC was determined in animals pretreated with a combination of a daily dose of GAL (200 mg/kg b.wt., i.p. for 5 days), EE (5 mg/kg b.wt. s.c. for 5 days), uridine (0.9 g/kg b.wt., i.p. for 5 days), or vehicle (propylene glycol). SRM values were calculated as the mean of the three highest consecutive 10-min biliary secretory rates recorded over the whole TUDC infusion periods. Results are expressed as mean ± S.E. for four animals per group.