TABLE 7

Accuracy of human MRT predictions from preclinical species using various methodologies


Method

Qualitative Number Correct (%)

Quantitative (2-fold) Number Correct (%)

MAE (%)
min
Rat volume and LBF 17 (81.0) 13 (61.9) 1074 (43.6)
Dog volume and LBF 13 (61.9) 14 (66.7) 2019 (81.8)
Monkey volume and LBF 19 (90.5) 12 (57.1) 2134 (86.5)
Three-species allometry
12 (57.1)
9 (38.1)
2428 (98.42)