Subject No. | mRNA Expression Level (copy/ng total RNA) | Ratio | ||||||
---|---|---|---|---|---|---|---|---|
OATP-B | OATP-D | OATP-E | Villin | OATP-B/Villin | ||||
1 | 120 | 29 | 3.5 | 500 | 0.24 | |||
2 | 327 | 100 | 14.6 | 942 | 0.35 | |||
3 | 317 | 112 | 10.0 | 544 | 0.58 | |||
4 | 254 | 83 | 5.9 | 746 | 0.34 | |||
5 | 406 | 73 | 6.8 | 795 | 0.51 | |||
6 | 207 | 46 | 3.2 | 462 | 0.45 | |||
7 | 414 | 74 | 6.4 | 545 | 0.76 | |||
9 | 469 | 73 | 9.5 | 838 | 0.56 | |||
10 | 164 | 41 | 8.1 | 564 | 0.29 | |||
11 | 239 | 112 | 9.7 | 751 | 0.32 | |||
12 | 183 | 62 | 9.5 | 563 | 0.33 | |||
13 | 102 | 77 | 9.0 | 750 | 0.14 | |||
14 | 751 | 74 | 12.0 | 597 | 1.26 | |||
Mean | 304 | 74* | 8.3* | 661 | 0.47 | |||
S.D. (n = 13) | 177 | 25 | 3.2 | 149 | 0.29 | |||
Caco-2 cells (mean, n = 2) | 9,030 | 34.9 | 154 | 925 | 9.76 |
↵* Significantly different from OATP-B (p < 0.05).