Subject No. (Genotype) | Debrisoquine | 4-Hydroxy-debrisoquine | 3,4-Dehydro-debrisoquine |
---|---|---|---|
1 (*1/*1) | 4.3 | 6.6 | 1.3 |
2 (*1/*1) | 1.1 | 3.6 | 2.7 |
3 (*1/*1) | 7.6 | 9.2 | 1.1 |
4 (*1/*1) | 1.0 | 2.1 | 0 |
5 (*1/*1) | 2.7 | 16.2 | 2.2 |
6 (*1/*1) | 1.7 | 6.2 | 4.0 |
7 (*1/*1) | 1.9 | 4.7 | 0 |
8 (*1/*1) | 6.0 | 11.2 | 8.9 |
9 (*1/*1) | 7.3 | 4.9 | 2.4 |
Mean ± S.E.M. | 3.7 ± 0.9 | 7.2 ± 1.4 | 2.5 ± 0.9 |
10 (*4/*4) | 33.8 | 0.3 | 0 |
11 (*4/*4) | 14.2 | <0.2 | 0 |
12 (*4/*4) | 9.4 | <0.08 | 0.4 |
13 (*4/*4) | 20.3 | <0.2 | 0 |
Mean ± S.E.M. | 19.5 ± 5.3 | 0.2 ± 0.1 | 0.1 ± 0.1 |
Significance (P) (Mann-Whitney U test)
|
0.0014
|
0.0014
|
0.025
|