Physiological values for tissue volumes and blood flow in rat and human
Default values taken from Gastroplus software 5.10.0 generic rat and human PBPK model.
Tissue | Rat | Human | ||||
|---|---|---|---|---|---|---|
| Blood Flow | Volume | Blood Flow | Volume | |||
| ml/min | ml | l/min | liters | |||
| Lung | 53.0 | 2.10 | 6.08 | 1.11 | ||
| Spleen | 0.600 | 0.600 | 0.184 | 0.184 | ||
| Liver | 13.8 | 10.3 | 1.50 | 1.63 | ||
| ACAT gut | 7.50 | 0.836 | ||||
| Adipose | 0.400 | 10.0 | 0.605 | 30.3 | ||
| Muscle | 7.50 | 122 | 0.622 | 20.7 | ||
| Heart | 3.90 | 1.20 | 0.230 | 0.315 | ||
| Brain | 1.30 | 1.24 | 0.882 | 1.73 | ||
| Kidney | 9.20 | 3.70 | 1.02 | 0.277 | ||
| Skin | 5.80 | 40.0 | 0.235 | 1.96 | ||
| Testes | 0.500 | 2.50 | 0.007 | 0.032 | ||
| Red marrow | 1.30 | 1.33 | 0.354 | 1.18 | ||
| Yellow marrow | 0.275 | 2.81 | 0.098 | 3.28 | ||
| Rest of body | 9.01 | 41.5 | 0.529 | 17.6 | ||
| Arterial blood | 53.0 | 5.60 | 6.08 | 2.21 | ||
| Venous blood | 53.0 | 11.3 | 6.08 | 4.42 | ||