Chemical names for tofisopam and its primary metabolites
Compound | Chemistry | Chemical Name |
|---|---|---|
| Tofisopam | Parent | 1-(3,4-Dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine |
| M1 | Demethylated at the 7-position of the benzodiazepine ring | 1-(3,4-Dimethoxyphenyl)-5-ethyl-7-hydroxy-8-methoxy-4-methyl-5H-2,3-benzodiazepine |
| M2 | Demethylated at the 8-position of the benzodiazepine ring | 1-(3,4-Dimethoxyphenyl)-5-ethyl-8-hydroxy-7-methoxy-4-methyl-5H-2,3-benzodiazepine |
| M3 | Demethylated at the 4-position of the phenyl ring | 1-(4-Hydroxy-3-methoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine |
| M4 | Demethylated at the 3-position of the phenyl ring | 1-(3-Hydroxy-4-methoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine |
| M5 | Demethylated at the 4-position of the phenyl ring and the 7-position of the benzodiazepine ring | 1-(4-Hydroxy-3-methoxyphenyl)-5-ethyl-7-hydroxy-8-methoxy-4-methyl-5H-2,3-benzodiazepine |
| M6 | Demethylated at the 3-position of the phenyl ring and the 7-position of the benzodiazepine ring | 1-(3-Hydroxy-4-methoxyphenyl)-5-ethyl-7-hydroxy-8-methoxy-4-methyl-5H-2,3-benzodiazepine |