Lisdexamfetamine | Isoform | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CYP1A2 | CYP2A6 | CYP2B6 | CYP2C9 | CYP2C19 | CYP2D6 | CYP3A (MDZ) | CYP3A4 (6βT) | ||||||||
0.01 μM | 99.6 | 102 | 101 | 96.6 | 95.2 | 98.4 | 107 | 97.0 | |||||||
0.1 μM | 99.7 | 96.7 | 99.3 | 93.6 | 98.4 | 98.3 | 111 | 94.5 | |||||||
1 μM | 97.8 | 101 | 101 | 91.4 | 102 | 101 | 95.4 | 82.4 | |||||||
10 μM | 95.1 | 98.2 | 88.9 | 90.6 | 99.6 | 97.8 | 98.6 | 94.6 | |||||||
100 μM | 94.2 | 92.5 | 90.8 | 89.0 | 87.3 | 90.0 | 92.1 | 101 |