Time-averaged concentration for CYP1A2 inactivators
Furafylline concentrations were unchanged throughout the incubation at all concentrations.
Initial Inactivator Concentration | Time-Averaged Concentration | |
|---|---|---|
| μM | μM | |
| Resveratrol | 4 | 3.3 |
| 6 | 4.7 | |
| 10 | 8.7 | |
| 15 | 11 | |
| 40 | 34 | |
| 60 | 40 | |
| 80 | 60 | |
| Oltipraz | 0.5 | 0.3 |
| 1 | 0.5 | |
| 2 | 1.2 | |
| 5 | 3.5 | |
| 7.5 | 5.6 | |
| 10 | 7.9 | |
| 20 | 18 | |
| Dihydralazine | 5 | 2.1 |
| 10 | 4.6 | |
| 15 | 5.4 | |
| 25 | 8.5 | |
| 75 | 49 | |
| 100 | 66 | |
|
| 150 | 114 |