Distribution (nmol-Eq BGE/g tissue ± S.D., n = 4 or 5) of BGE-derived radioactivity 24 h after a single 200-mg/kg p.o. dose
Tissuea | Male Rat | Female Rat | Male Mouse | Female Mouse |
|---|---|---|---|---|
| Blood | 39.4 ± 1.3 | 35.7 ± 3.5 | 18.1 ± 1.6 | 16.0 ± 2.3 |
| Plasma | 40.4 ± 2.9 | 38.7 ± 2.9 | 26.8 ± 4.8 | 18.6 ± 3.9 |
| Liver | 125 ± 9.5 | 150 ± 22 | 97.4 ± 15.2 | 75.9 ± 3.8 |
| Kidney | 97.2 ± 24.6 | 71.3 ± 5.0 | 128 ± 18 | 42.9 ± 5.5 |
| Lung | 69.3 ± 7.5 | 61.8 ± 2.8 | 44.1 ± 5.13 | 42.4 ± 4.2 |
| Muscle | 52.0 ± 40.9 | 11.7 ± 1.3 | 11.7 ± 1.4 | 15.0 ± 2.6 |
| Skin | 49.7 ± 3.5 | 36.7 ± 4.9 | 38.2 ± 3.4 | 38.2 ± 4.1 |
| Fat | 182 ± 95.7 | 40.0 ± 11.8 | 15.9 ± 2.3 | 32.9 ± 8.8 |
| Brain | 21.8 ± 2.2 | 16.8 ± 3.0 | 27.9 ± 36.5 | 11.5 ± 1.6 |
| Forestomach | 323 ± 29 | 394 ± 79 | 1750 ± 230 | 1770 ± 220 |
| Glandular stomach | 82.4 ± 18.4 | 74.3 ± 18.0 | 171 ± 21.6 | 184 ± 61 |
| Small intestine | 351 ± 164 | 117 ± 9.8 | 80.0 ± 5.8 | 65.7 ± 5.7 |
| Large intestine | 351 ± 154 | 175 ± 44 | 68.2 ± 6.1 | 50.1 ± 7.6 |
↵ a Tissues listed under Materials and Methods but not appearing in the Table contained 0.01% or less of the dose.