Subject | Dose | PABA Recovery | Urinary Drug Excretion | Δ Cu | Δ Zn | ||||
---|---|---|---|---|---|---|---|---|---|
TETA | MAT | DAT | |||||||
mg | % | μmol/day | μmol/day | ||||||
Dia1 | 300 a | 64.3 | 34.7 | 144 | 30.9 | 1.92 | -3.42 | ||
600 | 63.2 | 237 | 378 | 49.4 | 4.99 | 15.4 | |||
1200 | 17.6 | 50.0 | 79.9 | 40.0 | 1.83 | -8.26 | |||
2400 | 35.7 | 767 | 981 | 225 | 13.1 | 59.8 | |||
Dia2 | 300 | 83.6 | 5.46 | 108 | 13.6 | 0.511 | -2.18 | ||
600 | 117 | 10.2 | 152 | 81.1 | 0.969 | 9.13 | |||
1200 | 108 | 46.2 | 511 | 192 | 2.33 | 20.0 | |||
2400 | 92.0 | 120 | 659 | 115 | 3.66 | 31.7 | |||
Dia3 | 300 | 85.1 | 0.240 | 60.6 | 33.0 | 0.266 | 5.16 | ||
600 | 98.8 | 8.12 | 156 | 236 | 0.879 | 5.67 | |||
1200 | 93.5 | 37.6 | 389 | 170 | 2.38 | 9.31 | |||
2400 | 94.6 | 144 | 1068 | 217 | 6.87 | 45.9 | |||
Dia4 | 300 | 66.7 | 0.122 | 37.7 | 29.3 | 0.367 | 3.55 | ||
600 | 7.60 | 5.34 | 205 | 174 | 1.24 | 6.48 | |||
1200 | 53.3 | 22.0 | 418 | 324 | 1.88 | 25.2 | |||
2400 | 94.6 | 103 | 1057 | 320 | 7.69 | 60.6 | |||
Dia5 | 300 | 75.5 | 2.16 | 105 | 56.6 | 0.213 | -5.29 | ||
600 | 84.9 | 6.26 | 245 | 110 | 0.639 | 2.54 | |||
1200 | 91.6 | 21.8 | 394 | 93.6 | 1.91 | 6.74 | |||
2400 | 2.50 | 62.8 | 687 | 248 | 1.80 | 12.0 | |||
Dia6 | 300 | 81.1 | 4.38 | 51.9 | 20.6 | 0.947 | 2.28 | ||
600 | 93.3 | 12.7 | 74.3 | 20.6 | 1.11 | 6.89 | |||
1200 | 83.7 | 32.4 | 152 | 47.5 | 1.60 | 8.32 | |||
2400 | 79.4 | 114 | 372 | 131 | 3.62 | 15.2 | |||
Dia7 | 300 | 95.8 | 7.07 | 48.9 | 14.7 | 1.83 | 5.05 | ||
600 | 101 | 17.2 | 157 | 25.8 | 1.48 | 7.34 | |||
1200 | 89.7 | 62.9 | 350 | 79.9 | 3.35 | 25.8 | |||
| 2400 | 85.4 | 146 | 601 | 98.8 | 6.62 | 50.2 |
Dia, diabetic.
↵ a Italicized numbers represent excluded data points.