Total recovery of LSB, M1, M2, and M3 excreted in bile after intravenous administration of 60 mg/kg S. miltiorrhiza depside salts in Sprague-Dawley rats
Time after Administration | Ratio to LSB Administration | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| LSB | M1 | M2 | M3 | total | |||||
| % | |||||||||
| 0 to 2 h | 13.7 ± 4.1 | 38.6 ± 2.7 | 24.3 ± 5.9 | 5.5 ± 2.3 | 82.1 ± 6.6 | ||||
| 2 to 6 h | 0.10 ± 0.03 | 1.28 ± 0.19 | 2.08 ± 0.52 | 0.96 ± 0.59 | 4.43 ± 1.07 | ||||
| 0 to 6 h | 13.8 ± 4.5 | 39.9 ± 3.0 | 26.3 ± 6.9 | 6.4 ± 3.2 | 86.5 ± 7.9 | ||||