Glucuronidation | n | Substrate | r | P |
---|---|---|---|---|
μM | ||||
Bilirubin glucuronidation | 11 | 10 | 0.963 | <0.0001 |
β-Estradiol 3-glucuronidation | 22 | 100 | 0.965 | <0.0001 |
Etoposide glucuronidation | 11 | 400 | 0.829 | <0.01 |
Trifluoperazine glucuronidation | 22 | 100 | 0.179 | N.S. |
Propofol glucuronidation | 22 | 30 | 0.449 | <0.05 |
Morphine 3-glucuronidation | 11 | 250 | 0.257 | N.S. |
n, number of individual human liver microsomes; N.S., not significant.