Accuracy of Ptp predictions using tissue-composition based equations
For details on methods Vd1 and Vd2, see Materials and Methods.
afe | rmse | Percentage within 2-fold Error | Percentage within 2.5-fold Error | Percentage within 3-fold Error | |
|---|---|---|---|---|---|
| Method Vd1 | |||||
| Muscle (n = 20) | 1.28 | 3.46 | 63.2 | 84.2 | 89.5 |
| Liver (n = 24) | 1.44 | 37.6 | 45.8 | 54.2 | 62.5 |
| Lung (n = 21) | 1.95 | 61.1 | 42.9 | 47.6 | 47.6 |
| Heart (n = 19) | 1.38 | 7.48 | 52.6 | 63.2 | 84.2 |
| Brain (n = 21) | 1.61 | 6.78 | 52.4 | 57.1 | 61.9 |
| Kidney (n = 22) | 1.03 | 9.22 | 72.7 | 77.3 | 81.8 |
| Method Vd2 | |||||
| Muscle (n = 20) | 1.28 | 3.10 | 63.2 | 84.2 | 84.2 |
| Liver (n = 24) | 2.28 | 40.6 | 29.2 | 41.7 | 54.2 |
| Lung (n = 21) | 2.41 | 63.9 | 19.0 | 33.3 | 47.6 |
| Heart (n = 19) | 1.12 | 7.18 | 57.9 | 63.2 | 68.4 |
| Brain (n = 21) | 9.54 | 13.6 | 9.52 | 14.3 | 23.8 |
| Kidney (n = 22) | 1.99 | 11.8 | 59.1 | 59.1 | 63.6 |