Radiolabeled mass balance of CP-122,721 in humans administered a 30-mg (free base)/kg p.o. dose
Subject No. | Percentage of Total 14C Excreted from 0 to 312 h Postdose | ||||
|---|---|---|---|---|---|
| Urine | Feces | Total | |||
| EMs | |||||
| 1 | 78.8 | 9.4 | 88.2 | ||
| 2 | 85.2 | 2.3 | 87.5 | ||
| 3 | 74.7 | 9.6 | 84.3 | ||
| 4 | 84.0 | 4.9 | 88.9 | ||
| Mean | 80.7 | 6.6 | 87.2 | ||
| S.D. | 4.9 | 3.6 | 2.0 | ||
| PMs | |||||
| 5 | 65.0 | 6.9 | 71.9 | ||
| 6 | 77.2 | 6.9 | 84.1 | ||
|
Mean
|
71.1
|
6.9
|
78.0
| ||