Inhibition constants of TG100435 and TG100855 to different protein tyrosine kinases
PTK | Ki (TG100435) | Ki (TG100855) | |
|---|---|---|---|
| nM | |||
| Src | 28.1 ± 2.1 | 7.22 ± 2.46 | |
| Lyn | 25.9 ± 1.2 | 4.19 ± 0.66 | |
| Abl | 19.4 ± 3.5 | 2.04 ± 0.28 | |
| Yes | 12.9 ± 1.9 | 5.97 ± 0.43 | |
| Lck | 29.4 ± 3.4 | 11.7 ± 1.6 | |
| EphB4 | 63.8 ± 5.2 | 7.27 ± 0.55 | |