TABLE 1

Genes differentially expressed in LNCaP treated with valproic acid


Gene

Accession Number

Gene Title

-Fold Change
Down-Regulated Genes
ARA24 NM_006325 Androgen receptor coregulator −2.89
AR NM_000044 Androgen receptor −1.64
CYP11A NM_000781 Cytochrome P450, family 11, subfamily A, polypeptide 1 −1.73
KLF6 NM_001300 Krappel-like factor 6 −1.63
CG1-10 NM_0152940 CGI-10 protein −1.69
FDPS NM_002004 Farnesyl diphosphate synthase-like 1 (farnesyl pyrophosphate synthetase-like 1, cholesterol-repressible protein 39A) −2.02
IDI1 NM_004508 Isopentenyl-diphosphate delta isomerase 1 −2.01
PART1 NM_016590 Prostate androgen-regulated transcript 1 −2.01
PDE5A NM_001083 Phosphodiesterase 5A, cGMP-specific −1.94
PSA NM_001648 Kallikrein 3, (prostate-specific antigen) −6.19
Up-Regulated Genes
UGT2B7 NM_001074 UDP-glucuronosyltransferase 2 family, polypeptide B7 1.90
UGT2B11
NM_0010173
UDP-glucuronosyltransferase 2 family, polypeptide B11
2.46
  • FDPS, farnesyl pyrophosphate synthase; IDI1, isopentenyl-diphosphate δ -isomerase; PART1, prostate androgen-regulated transcript.