TABLE 1

Michaelis constants and peak area ratios for 9cUAB30 metabolites

Relative Vmax values are represented by the peak area ratio of the metabolite compared with an internal standard.


Parameters

Metabolites of 9cUAB30
M1
M2
M3
M4
M5
M7
M8
Relative Vmax 0.19 0.14 0.49 0.40 0.04 0.008 0.08
Km (μM)
25.2 ± 6.1
0.97 ± 0.4
9.7 ± 3.2
15.1 ± 6.3
9.7 ± 2.6
3.8 ± 1.8
16.5 ± 7.8