Subject No. | MK-0524 | Radioactivity | MK-0524/Radioactivity | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AUC0-∞ | Cmax | Tmax | AUC0-∞ | Cmax | Tmax | AUC0-∞ Ratio | Cmax Ratio | ||||||
μM · h | μM | h | μM Eq · h | μM Eq | h | ||||||||
001 | 10.8 | 1.76 | 1.5 | 31.6 | 3.60 | 1.5 | 0.34 | 0.49 | |||||
002 | 12.6 | 3.59 | 1.0 | 34.2 | 6.05 | 1.0 | 0.37 | 0.59 | |||||
003 | 10.3 | 1.98 | 1.0 | 33.5 | 4.67 | 1.5 | 0.31 | 0.42 | |||||
004 | 4.32 | 1.27 | 1.5 | 29.5 | 5.17 | 1.5 | 0.15 | 0.25 | |||||
005 | 12.9 | 2.71 | 1.0 | 48.5 | 6.44 | 1.0 | 0.27 | 0.42 | |||||
006 | 13.6 | 2.73 | 1.0 | 33.3 | 4.50 | 1.5 | 0.41 | 0.61 | |||||
AM | 10.8 | 2.34 | 1.2 | 35.1 | 5.07 | 1.3 | |||||||
S.D. | 3.40 | 0.83 | 0.3 | 6.80 | 1.05 | 0.3 |
|
|
AM, arithmetic mean.