pH 5.5 | pH 7.0 | |||||
---|---|---|---|---|---|---|
EC50 | Maximal -Fold Activation | EC50a | Maximal -Fold Activation | |||
μM | μM | |||||
Sulfasalazine | 0.6 ± 0.1 | 2.9 ± 0.6 | 0.6 ± 0.1 | 3.4 ± 1.0 | ||
Prazosin | 4.5 ± 0.7 | 2.3 ± 0.6 | 2.5 ± 0.7 | 2.0 ± 0.6 | ||
Topotecan | 25 ± 7.1 | 2.5 ± 0.2 | 17.5 ± 3.5 | 2.4 ± 1.1 |
EC50, the concentration of half-maximal stimulation of the compound tested.