TABLE 4

Relative abundance of urinary and fecal metabolites of torcetrapib in male and female rats after oral administration of [14C]torcetrapib-A


Metabolites

Male Rats

Female Rats

Urine
Feces
Total
Urine
Feces
Total
Torcetrapib 33.6 33.6 39.3 39.3
M2 0.69 0.69 0.63 0.63
M4 11.9 11.9 9.63 9.63
M5 6.41 6.41 6.37 6.37
M7 6.5 6.5 7.12 7.12
M12 4.82 4.82 3.6 3.6
M13 6.75 6.75 2.03 2.03
M21 0.94 0.94 1.87 1.87
M22
1.98

1.98
3.75

3.75