Inhibition of metabolite production on the basal side by different treatments
Feruloyl-Glucuronidea | Dihydroferulic Acida | |
|---|---|---|
| Ibuprofenb | 37.7 ± 6.3* | 95.1 ± 17.3 |
| α-Cyano-4-hydroxycinnamic acidb | 114.7 ± 20.7 | 111.3 ± 10.0 |
| MK571c | 40.9 ± 3.6* | 64.6 ± 4.8* |
| Cyclosporin Ac | 117.5 ± 5.3* | 128.5 ± 6.3* |
↵* Significantly different from the control value (P < 0.05, t test)
↵ a Metabolites (in percentage of control), released on basal side after 1 h of incubation of the apical compartment with ferulic acid at 1 mM
↵ b 150 μM concentration of inhibitor on the apical side
↵ c 50 μM concentration of inhibitor on the basal side