TABLE 1

Pharmacokinetic parameters of [¹⁴C]dasatinib-equivalents in blood, milk, and plasma of lactating Sprague-Dawley rats on day 8 or 9 postpartum following a single p.o. dose of [¹⁴C]dasatinib (10 mg/kg, 300 μCi/kg)

	C_max	T_max	t_1/2 ^a	AUC_0-t	AUC_0-inf
	ng equivalents/g	h	h	ng equivalents × h/g	ng equivalents × h/g
Blood	92.5	4	6.8	1080	1190
Milk	2070	8	5.5	25,500	25,500
Plasma	96.0	1	7.6	1020	1150

↵ a t_1/2 values were calculated using three time points