Time Point | Oral (20 mg/kg) | Intravenous (5 mg/kg) | ||||
---|---|---|---|---|---|---|
Plasma | Brain | Plasma | Brain | |||
0.5 h | 12,400 ± 1900 | 22,800 ± 2400 | 3910 ± 250 | 8510 ± 630 | ||
1 h | 16,500 ± 2600 | 23,400 ± 3500 | 3770 ± 800 | 5340 ± 470 | ||
2 h | 14,000 ± 2400 | 20,100 ± 3800 | 867 ± 58 | 994 ± 538 | ||
4 h | 5950 ± 3950 | 4620 ± 3350 | 586 ± 118 | 323 ± 175 | ||
8 h | 661 ± 389 | 255 ± 225 | 145 ± 58 | 44 ± 6 |