NCBI: Homo sapiens genes—REFLIST (25,431) | Uploaded ANOVA Genes (2025) | No. of Genes Expected | Over/Under | P | |
---|---|---|---|---|---|
Biological process | |||||
Biological process unclassified | 11,321 | 423 | 728.74 | - | 1.11E-53 |
Nucleotide and nucleic acid metabolism | 3343 | 352 | 215.19 | + | 2.81E-19 |
Cell cycle | 1009 | 144 | 64.95 | + | 8.54E-17 |
Protein metabolism and modification | 3040 | 305 | 195.69 | + | 1.32E-13 |
Protein phosphorylation | 660 | 98 | 42.48 | + | 1.81E-11 |
Protein modification | 1157 | 141 | 74.48 | + | 1.54E-10 |
Other metabolism | 559 | 79 | 35.98 | + | 7.05E-09 |
Cell cycle control | 418 | 64 | 26.91 | + | 8.46E-08 |
Intracellular protein traffic | 1008 | 115 | 64.89 | + | 1.74E-07 |
Pre-mRNA processing | 291 | 49 | 18.73 | + | 4.76E-07 |
Sensory perception | 506 | 7 | 32.57 | - | 1.76E-06 |
Intracellular signaling cascade | 871 | 101 | 56.07 | + | 3.29E-06 |
Mitosis | 382 | 55 | 24.59 | + | 9.83E-06 |
G protein-mediated signaling | 834 | 20 | 53.68 | - | 1.70E-05 |
DNA metabolism | 360 | 51 | 23.17 | + | 4.66E-05 |
mRNA splicing | 214 | 36 | 13.78 | + | 7.67E-05 |
Cell adhesion-mediated signaling | 379 | 4 | 24.4 | - | 7.73E-05 |
Stress response | 200 | 33 | 12.87 | + | 2.52E-04 |
Cell communication | 1213 | 43 | 78.08 | - | 1.02E-03 |
Apoptosis | 531 | 60 | 34.18 | + | 1.02E-03 |
Lipid, fatty acid, and steroid metabolism | 770 | 79 | 49.57 | + | 1.66E-03 |
DNA repair | 169 | 28 | 10.88 | + | 1.88E-03 |
Carbohydrate metabolism | 592 | 64 | 38.11 | + | 2.00E-03 |
Amino acid metabolism | 230 | 32 | 14.81 | + | 2.03E-03 |
Oncogenesis | 472 | 53 | 30.38 | + | 3.33E-03 |
General vesicle transport | 251 | 35 | 16.16 | + | 4.24E-03 |
Protein folding | 186 | 28 | 11.97 | + | 7.22E-03 |
mRNA transcription | 1914 | 167 | 123.2 | + | 7.64E-03 |
Cell surface receptor signal transduction | 1638 | 69 | 105.44 | - | 9.35E-03 |
Phosphate metabolism | 117 | 19 | 7.53 | + | 9.50E-03 |
Cell adhesion | 622 | 20 | 40.04 | - | 9.82E-03 |
Cell proliferation and differentiation | 1028 | 93 | 66.17 | + | 2.61E-02 |
Antioxidation and free radical removal | 38 | 10 | 2.45 | + | 3.34E-02 |
Purine metabolism | 65 | 13 | 4.18 | + | 5.90E-02 |
Amino acid catabolism | 50 | 11 | 3.22 | + | 7.43E-02 |
Cell structure and motility | 1148 | 99 | 73.9 | + | 7.69E-02 |
Neuronal activities | 569 | 21 | 36.63 | - | 1.05E-01 |
Cytokinesis | 115 | 18 | 7.4 | + | 1.31E-01 |
Protein targeting and localization | 253 | 28 | 16.29 | + | 1.53E-01 |
Other intracellular signaling cascade | 225 | 28 | 14.48 | + | 1.95E-01 |
Protein targeting | 113 | 17 | 7.27 | + | 2.02E-01 |
Endocytosis | 277 | 32 | 17.83 | + | 2.14E-01 |
DNA replication | 155 | 21 | 9.98 | + | 2.16E-01 |
RNA localization | 33 | 8 | 2.12 | + | 2.29E-01 |
Pathway | |||||
Unclassified | 22,565 | 1340 | 1452.51 | - | 2.64E-14 |
Ubiquitin proteasome pathway | 89 | 23 | 5.73 | + | 5.75E-06 |
PDGF signaling pathway | 189 | 32 | 12.17 | + | 2.05E-04 |
Apoptosis signaling pathway | 131 | 25 | 8.43 | + | 3.75E-04 |
p53 pathway | 136 | 25 | 8.75 | + | 7.07E-04 |
FGF signaling pathway | 148 | 25 | 9.53 | + | 2.84E-03 |
EGF receptor signaling pathway | 150 | 25 | 9.66 | + | 3.53E-03 |
Parkinson's disease | 106 | 20 | 6.82 | + | 4.18E-03 |
Huntington's disease | 172 | 27 | 11.07 | + | 4.72E-03 |
T cell activation | 111 | 20 | 7.15 | + | 7.80E-03 |
Angiogenesis | 229 | 32 | 14.74 | + | 8.45E-03 |
Ras pathway | 91 | 17 | 5.86 | + | 1.79E-02 |
p53 pathway feedback loops 2 | 66 | 14 | 4.25 | + | 1.93E-02 |
Cell cycle | 29 | 9 | 1.87 | + | 1.98E-02 |
TGF—β signaling pathway | 154 | 23 | 9.91 | + | 3.49E-02 |
Insulin/IGF pathway—MAP kinase cascade | 49 | 10 | 3.15 | + | 2.19E-01 |
B cell activation | 86 | 14 | 5.54 | + | 2.45E-01 |
Oxidative stress response | 69 | 12 | 4.44 | + | 2.98E-01 |
Toll receptor signaling pathway | 71 | 12 | 4.57 | + | 3.75E-01 |
Circadian clock system | 16 | 5 | 1.03 | + | 5.77E-01 |
5—Hydroxytryptamine degradation | 17 | 5 | 1.09 | + | 7.42E-01 |
Cholesterol biosynthesis | 11 | 4 | 0.71 | + | 8.36E-01 |
Axon guidance mediated by netrin | 40 | 5 | 2.57 | + | 1.00E+00 |
Axon guidance mediated by Slit/Robo | 35 | 3 | 2.25 | + | 1.00E+00 |
Axon guidance mediated by semaphorins | 46 | 5 | 2.96 | + | 1.00E+00 |
Alzheimer disease-presenilin pathway | 143 | 9 | 9.2 | - | 1.00E+00 |
Alzheimer disease-amyloid secretase pathway | 77 | 3 | 4.96 | - | 1.00E+00 |
Adrenaline and noradrenaline biosynthesis | 30 | 4 | 1.93 | + | 1.00E+00 |
mRNA splicing | 11 | 1 | 0.71 | + | 1.00E+00 |
PDGF, platelet-derived growth factor; FGF, fibroblast growth factor; EGF, epidermal growth factor; IFG, insulin-like growth factor; TGF, transforming growth factor; MAP, mitogen-activated protein.