TABLE 1

Percentage of the radioactive dose recovered in urine, bile, and feces during 0- to 48-h collections after an oral dose of [¹⁴C]razaxaban to rats and dogs

Species	No. of Animals	Dose^a	Matrix^b	Average Recovery
		mg/kg		% of dose
BDC rat	3	300	Urine	11.0
			Feces	18.1
			Bile	34.2
			Total	63
Intact rat	3	300	Urine	3.4
			Feces	88.1
			Total	91.5
BDC dog	2	20	Urine	13.6
			Feces	25.0
			Bile	43.9
			Total	84
Intact dog	2	20	Urine	5.0
			Feces	75.5
			Total	79.5

↵ a Dose was prepared as a suspension in 0.5% methycellulose at 25 mg/ml.
↵ b Collected 0 to 48 h postdose.