Compound | IC50 | ||
---|---|---|---|
E217βG Uptake | LTC4 Uptake | ||
μM | |||
5-GS-N-Me-α-MeDA | 31 ± 9 (3) | 137 ± 2 (3) | |
2-GS-CA | 3.1 ± 1.2 (3) | 20 ± 14 (3) | |
2-OH-1-GS-E2 | 0.27 ± 0.11 (4) | 1.2 ± 0.2 (3) | |
2-OH-1-GS-E1 | 0.29 ± 0.16 (3) | 0.5, 1.0 | |
2-OH-4-GS-E2 | 0.08 ± 0.05 (3) | 0.2, 0.8 | |
4-OH-2-GS-E2 | 0.23 ± 0.14 (4) | 0.6, 1.0 |