TABLE 7
Metabolite profiles in human hepatic in vitro systems using [
14
C]
1
(20 μM)
System
Compound (% of Total
14
C)
1
M1
2
3
M5
HLMs
+NADPH
61
7
8
14
9
-NADPH
51
—
13
36
—
Hepatocytes
57
—
32
11
—
Mitochondria
76
—
17
6
—
—, not detected.