Kinetic parameters for the cosubstrate UDPGA in the glucuronidation of three OH-PCBs
Results are mean ± S.D.; n = 4.
| OH-PCB Concentration | Vmax (Apparent) | Km (Apparent) | |
|---|---|---|---|
| μM | nmol/min/mg | μM | |
| Liver | |||
| 4′-OH-CB35 | 500 | 0.87 ± 0.20 | 697 ± 246 |
| 4′-OH-CB72 | 500 | 0.60 ± 0.10 | 684 ± 323 |
| Intestine | |||
| 4′-OH-CB69 | 200 | 0.20 ± 0.11 | 27 ± 14 |